Kentucky mother and daughter turn down $26.5MILLION to sell their farms to secretive tech giant that wants to build data center there Horrifying next twist in the Alexander brothers case: MAUREEN CALLAHAN exposes an unthinkable perversion that's been hiding in plain sight Hollywood icon who starred in Psycho after Hitchcock dubbed her'my new Grace Kelly' looks incredible at 95 Kylie Jenner's total humiliation in Hollywood: Derogatory rumor leaves her boyfriend's peers'laughing at her' behind her back Tucker Carlson erupts at Trump adviser as she hurls'SLANDER' claim linking him to synagogue shooting Ben Affleck'scores $600m deal' with Netflix to sell his AI film start-up Long hair over 45 is ageing and try-hard. I've finally cut mine off. Alexander brothers' alleged HIGH SCHOOL rape video: Classmates speak out on sickening footage... as creepy unseen photos are exposed Heartbreaking video shows very elderly DoorDash driver shuffle down customer's driveway with coffee order because he is too poor to retire Amber Valletta, 52, was a '90s Vogue model who made movies with Sandra Bullock and Kate Hudson, see her now Model Cindy Crawford, 60, mocked for her'out of touch' morning routine: 'Nothing about this is normal' Icebergs, penguins and 23ft waves: Our science editor reviews a'once in a lifetime' trip to Antarctica that involved crossing the world's most terrifying stretch of ocean READ MORE: £30,000 job with all living costs paid...but it's in the Antarctic'If you can explain Antarctica, you've never been there.' That was the quote from our captain, Jorn Bowitz, as we set off on our voyage to the White Continent. But you really can visit the magical place - the coldest, windiest and driest on Earth - for yourself.

Sampling useful three-dimensional molecular structures along with their most favorable conformations is a key challenge in drug discovery. Current state-of-the-art 3D de-novo design flow matching or diffusion-based models are limited to generating a single conformation. However, the conformational landscape of a molecule determines its observable properties and how tightly it is able to bind to a given protein target. By generating a representative set of low-energy conformers, we can more directly assess these properties and potentially improve the ability to generate molecules with desired thermodynamic observables. Towards this aim, we propose FlexiFlow, a novel architecture that extends flow-matching models, allowing for the joint sampling of molecules along with multiple conformations while preserving both equivariance and permutation invariance. We demonstrate the effectiveness of our approach on the QM9 and GEOM Drugs datasets, achieving state-of-the-art results in molecular generation tasks. Our results show that FlexiFlow can generate valid, unstrained, unique, and novel molecules with high fidelity to the training data distribution, while also capturing the conformational diversity of molecules. Moreover, we show that our model can generate conformational ensembles that provide similar coverage to state-of-the-art physics-based methods at a fraction of the inference time. Finally, FlexiFlow can be successfully transferred to the protein-conditioned ligand generation task, even when the dataset contains only static pockets without accompanying conformations.

Motion instruction is a crucial task that helps athletes refine their technique by analyzing movements and providing corrective guidance. Although recent advances in multimodal models have improved motion understanding, generating precise and sport-specific instruction remains challenging due to the highly domain-specific nature of sports and the need for informative guidance. We propose CoachMe, a reference-based model that analyzes the differences between a learner's motion and a reference under temporal and physical aspects. This approach enables both domain-knowledge learning and the acquisition of a coach-like thinking process that identifies movement errors effectively and provides feedback to explain how to improve. In this paper, we illustrate how CoachMe adapts well to specific sports such as skating and boxing by learning from general movements and then leveraging limited data. Experiments show that CoachMe provides high-quality instructions instead of directions merely in the tone of a coach but without critical information. CoachMe outperforms GPT-4o by 31.6% in G-Eval on figure skating and by 58.3% on boxing. Analysis further confirms that it elaborates on errors and their corresponding improvement methods in the generated instructions. You can find CoachMe here: https://motionxperts.github.io/

Modality fusion is a cornerstone of multimodal learning, enabling information integration from diverse data sources. However, vanilla fusion methods are limited by (1) inability to account for heterogeneous interactions between modalities and (2) lack of interpretability in uncovering the multimodal interactions inherent in the data. To this end, we propose I2MoE (Interpretable Multimodal Interaction-aware Mixture of Experts), an end-to-end MoE framework designed to enhance modality fusion by explicitly modeling diverse multimodal interactions, as well as providing interpretation on a local and global level. First, I2MoE utilizes different interaction experts with weakly supervised interaction losses to learn multimodal interactions in a data-driven way. Second, I2MoE deploys a reweighting model that assigns importance scores for the output of each interaction expert, which offers sample-level and dataset-level interpretation. Extensive evaluation of medical and general multimodal datasets shows that I2MoE is flexible enough to be combined with different fusion techniques, consistently improves task performance, and provides interpretation across various real-world scenarios. Code is available at https://github.com/Raina-Xin/I2MoE.

This thesis explores advanced approaches to improve explainability in computer vision by analyzing and modeling the features exploited by deep neural networks. Initially, it evaluates attribution methods, notably saliency maps, by introducing a metric based on algorithmic stability and an approach utilizing Sobol indices, which, through quasi-Monte Carlo sequences, allows a significant reduction in computation time. In addition, the EVA method offers a first formulation of attribution with formal guarantees via verified perturbation analysis. Experimental results indicate that in complex scenarios these methods do not provide sufficient understanding, particularly because they identify only "where" the model focuses without clarifying "what" it perceives. Two hypotheses are therefore examined: aligning models with human reasoning -- through the introduction of a training routine that integrates the imitation of human explanations and optimization within the space of 1-Lipschitz functions -- and adopting a conceptual explainability approach. The CRAFT method is proposed to automate the extraction of the concepts used by the model and to assess their importance, complemented by MACO, which enables their visualization. These works converge towards a unified framework, illustrated by an interactive demonstration applied to the 1000 ImageNet classes in a ResNet model.

For large groups, use the name of the group or consortium and include a full list of the authors and affiliations at the end of the main manuscript or in the Supplementary Materials. Abstract: How diverse are the outputs of large language models when diversity is desired? We examine the diversity of responses of various models to questions with multiple possible answers, comparing them with human responses. Our findings suggest that models' outputs are highly concentrated, reflecting a narrow, mainstream'worldview', in comparison to humans, whose responses exhibit a much longer-tail. We examine three ways to increase models' output diversity: 1) increasing generation randomness via temperature sampling; 2) prompting models to answer from diverse perspectives; 3) aggregating outputs from several models. A combination of these measures significantly increases models' output diversity, reaching that of humans. We discuss implications of these findings for AI policy that wishes to preserve cultural diversity, an essential building block of a democratic social fabric. Conversely, a lack of diversity can result in extremism and exclusion (e.g., 1, 2).

Large language models excel at creative generation but continue to struggle with the issues of hallucination and bias. While retrieval-augmented generation (RAG) provides a framework for grounding LLMs' responses in accurate and up-to-date information, it still raises the question of bias: which sources should be selected for inclusion in the context? And how should their importance be weighted? In this paper, we study the challenge of cross-lingual RAG and present a dataset to investigate the robustness of existing systems at answering queries about geopolitical disputes, which exist at the intersection of linguistic, cultural, and political boundaries. Our dataset is sourced from Wikipedia pages containing information relevant to the given queries and we investigate the impact of including additional context, as well as the composition of this context in terms of language and source, on an LLM's response. Our results show that existing RAG systems continue to be challenged by cross-lingual use cases and suffer from a lack of consistency when they are provided with competing information in multiple languages. We present case studies to illustrate these issues and outline steps for future research to address these challenges. We make our dataset and code publicly available at https://github.com/manestay/bordIRlines.

Deep reinforcement learning (DRL) has significantly advanced the field of combinatorial optimization (CO). However, its practicality is hindered by the necessity for a large number of reward evaluations, especially in scenarios involving computationally intensive function assessments. To enhance the sample efficiency, we propose a simple but effective method, called symmetric replay training (SRT), which can be easily integrated into various DRL methods. Our method leverages high-reward samples to encourage exploration of the under-explored symmetric regions without additional online interactions - free. Through replay training, the policy is trained to maximize the likelihood of the symmetric trajectories of discovered high-rewarded samples. Experimental results demonstrate the consistent improvement of our method in sample efficiency across diverse DRL methods applied to real-world tasks, such as molecular optimization and hardware design.

Boulders form from a variety of geological processes, which their size, shape, and orientation may help us better understand. Furthermore, they represent potential hazards to spacecraft landing that need to be characterized. However, mapping individual boulders across vast areas is extremely labor-intensive, often limiting the extent over which they are characterized and the statistical robustness of obtained boulder morphometrics. To automate boulder characterization, we use an instance segmentation neural network, Mask R-CNN, to detect and outline boulders in high-resolution satellite images. Our neural network, BoulderNet, was trained from a dataset of > 33,000 boulders in > 750 image tiles from Earth, the Moon, and Mars. BoulderNet not only correctly detects the majority of boulders in images, but it identifies the outline of boulders with high fidelity, achieving average precision and recall values of 72% and 64% relative to manually digitized boulders from the test dataset, when only detections with intersection-over-union ratios > 50% are considered valid. These values are similar to those obtained by human mappers. On Earth, equivalent boulder diameters, aspect ratios, and orientations extracted from predictions were benchmarked against ground measurements and yield values within 15%, 0.20, and 20 degrees of their ground-truth values, respectively. BoulderNet achieves better boulder detection and characterization performance relative to existing methods, providing a versatile open-source tool to characterize entire boulder fields on planetary surfaces.

Azure Cognitive Search (ACS) has emerged as a major contender in "Search as a Service" cloud products in recent years. However, one of the major challenges for ACS users is to improve the relevance of the search results for their specific usecases. In this paper, we propose a novel method to find the optimal ACS configuration that maximizes search relevance for a specific usecase (product search, document search...) The proposed solution improves key online marketplace metrics such as click through rates (CTR) by formulating the search relevance problem as hyperparameter tuning. We have observed significant improvements in real-world search call to action (CTA) rate in multiple marketplaces by introducing optimized weights generated from the proposed approach.